FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170

FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

IN VITRO ANTHELMINTIC ACTIVITY OF GOAT BILE CHEMICAL SUBSTANCES AGAINST Haemonchus contortus
Pages: 504-508
J. D. Habila1, J. I. Achika2*, A. J. Habila3, O. R. A. Iyun1 and N. Zubair


keywords: Albendazole, anthelmintic activity, egg hatching, goat bile, Haemonchus concortus

Abstract

Extracts of goat bile Chemicals substances were investigated for anthelmintic activity against Haemonchus concortus. Various concentrations (50, 100 and 200 mg/ml) of each extract of the bile were tested using the egg hatch assay and larval development assay. All extract tested showed 100% mortality at the end of 180 min of the test duration. While 0.25 mg/ml of albendazole the positive control showed 100% mortality after 120 min. The results of the egg hatch inhibition assay showed that at a concentration of 200 mg/ml, 65% of the eggs were inhibited from hatching by the bile extract. Albendazole inhibited 98% of the eggs from hatching at 0.25 mg/ml. Goat bile extract has potential as anthelmintic from nature, that can be explore in the search for natural remedy for parasitic affections.

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